System impacts of solar dynamic and growth power systems on space station

Concepts for the 1990's space station envision an initial operational capability with electrical power output requirements of approximately 75 kW and growth power requirements in the range of 300 kW over a period of a few years. Photovoltaic and solar dynamic power generation techniques are contenders for supplying this power to the space station. A study was performed to identify growth power subsystem impacts on other space station subsystems. Subsystem interactions that might suggest early design changes for the space station were emphasized. Quantitative analyses of the effects of power subsystem mass and projected area on space station controllability and reboost requirements were conducted for a range of growth station configurations. Impacts on space station structural dynamics as a function of power subsystem growth were also considered

An advanced technology space station for the year 2025, study and concepts

A survey was made of potential space station missions that might exist in the 2020 to 2030 time period. Also, a brief study of the current state-of-the-art of the major subsystems was undertaken, and trends in technologies that could impact the subsystems were reviewed. The results of the survey and study were then used to arrive at a conceptual design of a space station for the year 2025. Factors addressed in the conceptual design included requirements for artificial gravity, synergies between subsystems, and the use of robotics. Suggestions are made relative to more in-depth studies concerning the conceptual design and alternative configurations

Analysis of a rotating advanced-technology space station for the year 2025

An analysis is made of several aspects of an advanced-technology rotating space station configuration generated under a previous study. The analysis includes examination of several modifications of the configuration, interface with proposed launch systems, effects of low-gravity environment on human subjects, and the space station assembly sequence. Consideration was given also to some aspects of space station rotational dynamics, surface charging, and the possible application of tethers

Some operational aspects of a rotating advanced-technology space station for the year 2025

The study of an Advanced Technology Space Station which would utilize the capabilities of subsystems projected for the time frame of the years 2000 to 2025 is discussed. The study includes tradeoffs of nuclear versus solar dynamic power systems that produce power outputs of 2.5 megawatts and analyses of the dynamics of the spacecraft of which portions are rotated for artificial gravity. The design considerations for the support of a manned Mars mission from low Earth orbit are addressed. The studies extend to on-board manufacturing, internal gas composition effects, and locomotion and material transfer under artificial gravity forces. The report concludes with an assessment of technology requirements for the Advanced Technology Space Station

Stable U(IV) Complexes Form at High-Affinity Mineral Surface Sites

Uranium (U) poses a significant contamination hazard to soils, sediments, and groundwater due to its extensive use for energy production. Despite advances in modeling the risks of this toxic and radioactive element, lack of information about the mechanisms controlling U transport hinders further improvements, particularly in reducing environments where UIV predominates. Here we establish that mineral surfaces can stabilize the majority of U as adsorbed UIV species following reduction of UVI. Using X-ray absorption spectroscopy and electron imaging analysis, we find that at low surface loading, UIV forms inner-sphere complexes with two metal oxides, TiO2 (rutile) and Fe3O4 (magnetite) (at <1.3 U nm–2 and <0.037 U nm–2, respectively). The uraninite (UO2) form of UIV predominates only at higher surface loading. UIV–TiO2 complexes remain stable for at least 12 months, and UIV–Fe3O4 complexes remain stable for at least 4 months, under anoxic conditions. Adsorbed UIV results from UVI reduction by FeII or by the reduced electron shuttle AH2QDS, suggesting that both abiotic and biotic reduction pathways can produce stable UIV–mineral complexes in the subsurface. The observed control of high-affinity mineral surface sites on UIV speciation helps explain the presence of nonuraninite UIV in sediments and has important implications for U transport modeling

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.

Abstract BACKGROUND: The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. METHODS: We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. The coprimary hypotheses were that exenatide, administered once weekly, would be noninferior to placebo with respect to safety and superior to placebo with respect to efficacy. RESULTS: In all, 14,752 patients (of whom 10,782 [73.1%] had previous cardiovascular disease) were followed for a median of 3.2 years (interquartile range, 2.2 to 4.4). A primary composite outcome event occurred in 839 of 7356 patients (11.4%; 3.7 events per 100 person-years) in the exenatide group and in 905 of 7396 patients (12.2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interval [CI], 0.83 to 1.00), with the intention-to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo with respect to safety (P<0.001 for noninferiority) but was not superior to placebo with respect to efficacy (P=0.06 for superiority). The rates of death from cardiovascular causes, fatal or nonfatal myocardial infarction, fatal or nonfatal stroke, hospitalization for heart failure, and hospitalization for acute coronary syndrome, and the incidence of acute pancreatitis, pancreatic cancer, medullary thyroid carcinoma, and serious adverse events did not differ significantly between the two groups. CONCLUSIONS: Among patients with type 2 diabetes with or without previous cardiovascular disease, the incidence of major adverse cardiovascular events did not differ significantly between patients who received exenatide and those who received placebo. (Funded by Amylin Pharmaceuticals; EXSCEL ClinicalTrials.gov number, NCT01144338 .)

Experimental Study of a Single-Coil Induced-Electromotive-Force Plasma Accelerator

An experimental study was made of a single-coil induced-electromotive-force plasma accelerator which used a capacitor discharge for the driving force. A strong shock was observed from the first pulse with a velocity of 10(exp 6) centimeters per second. This shock was followed by three or four discharges which produced plasmoids moving at about 5 x 10(exp 6) centimeters per second. The efficiency of the accelerator was estimated to be about 3 percent in the production of the high-velocity plasmoids. Suggestions are made for the improvement of this type of accelerator